MatchstickTechnologies – Empowering Discovery

A multi-omics solution for every lab

Introducing PIXUL®

PIXUL® Multi-Sample Sonicator Highlights:

Process 1-96 samples in parallel to avoid sample shearing bottlenecks in NGS applications
Up to 12 unique sonication conditions can be run on a single 96-well plate, allowing simultaneous processing of multiple sample types and rapid optimization of conditions for difficult samples
Compatible with chromatin, DNA, RNA, and protein from purified samples, cells, or tissues
Inexpensive consumables keep sample processing costs low
A short 15-minute coupling fluid circulation avoids lengthy water degassing processes

Matchstick’s premier product, PIXUL® (stands for PIXelated ULtrasound), is a tool that processes each and every well of a 96-well microplate consistently and quickly. PIXUL® was designed completely from the ground up to provide the end user with an easy to use tool that is simple to set up, simple to use, and generates consistent results day in and day out. No other sample preparation platform out there can match the power and convenience of PIXUL®.

PIXUL® is an ultrasound-based sample preparation platform that fragments DNA and chromatin into tight but random distributions. Ultrasound is propagated into the well where microbubbles are formed. The intense collapse of these microbubbles lead to high shear stresses that fragment the samples into desired size ranges.

PIXUL® was conceived by an epigenetics researcher, and designed and built by ultrasound engineers to take the guesswork out of sample preparation. With PIXUL™, sample preparation is no longer an “art form”, but instead a simple device that gives repeatable results day in and day out.

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PIXUL® Testimonials

"PIXUL® can help you break through bottlenecks. PIXUL® is fast. PIXUL® is flexible, it is easy to use."

"Being able to load the material in a standard 96 well plate and not need a a lot of special consumables and reagents is definitely a great feature."

"PIXUL® is very simple, very rapid. It works with a standard 96 well plate. The whole process is very easy to do... Consistent shearing is key."

"PIXUL® provides simple, rapid and extremely consistent shearing of chromatin, DNA, RNA and proteins."

Using PIXUL® combined with Matrix ChIP we were able to study multiple antibodies on multiple samples and get results within hours. ... PIXUL® is a straightforward and user friendly instrument. I highly recommend PIXUL® for ChIP assays."

"Working with PIXUL® made our proteomics experiments of various cell type easy. ... PIXUL® gives us robust and reproducible lysis and excellent proteomics data."

"In the lab, I use state-of-the-art technologies: CryoCore Gun, PIXUL® and Matrix ChIP in 96-well plate format, ... These technologies have allowed me to obtain analyzable results on multiple epigenetic marks from multiple mouse organs in a single day."