Improved High-Throughput Sonication and Epigenetic Analysis with PIXUL-ChIP
Improved High-Throughput Sonication and Epigenetic Analysis with PIXUL-ChIP * ActiveMotif.com/blog-pixul-chip * Chromatin immunoprecipitation (ChIP) is the preferred method for studying the interaction between DNA and proteins. ChIP assays are particularly valuable in epigenetics research, where they can be used for studying the interaction of DNA with histones containing specific post-translational modifications and other regulatory proteins, […]
PIXUL-ChIP: integrated high-throughput sample preparation and analytical platform for epigenetic studies
Karol Bomsztyk, Daniel Mar, Yuliang Wang, Oleg Denisenko, Carol Ware, Christian D Frazar, Adam Blattler, Adam D Maxwell, Brian E MacConaghy, Thomas J Matula PIXUL-ChIP: integrated high-throughput sample preparation and analytical platform for epigenetic studies https://academic.oup.com/nar/article/47/12/e69/5423606 Abstract Chromatin immunoprecipitation (ChIP) is the most widely used approach for identification of genome-associated proteins and their modifications. We […]
A Guide To Sonication
https://www.lubio.ch/blog/a-guide-to-sonication/– Chromatin immunoprecipitation (ChIP) is the gold standard method to analyze DNA-binding proteins and their associated DNA sequences. It is widely used to study transcription factors and cofactors as well as histones and histone post-translational modifications. However, ChIP is a multi-step experiment where each step has to be carefully performed for successful results. In most […]
